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Thus, the beneficialeffect of b-blockers may be partially offset.

For initiation of treatment frequentlyone class of drugs are used. Additionalevidence obtained in animal models supports a significant contribution of the enzymaticconversion of azathioprine to mercaptopurine in vivo

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Delayed use of steroids has also beenlinked with hypertension and neurological abnor-malities.

After publication of these studies, rhBMP-2 use increased from0.7 to 25 % of all spinal fusions in the United States in a 5-year period ending in2006 (Caragee et al. History is not just a series of stories to entertain us but stories thatteach us how to continue in our daily life

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